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Capsules with a modified release hard gelatin, size 0, opaque, with red-brown cap and body ivory. The composition of the shell capsules: gelatin, titanium dioxide, iron oxide yellow (pigment), iron oxide red (dye). 1 capsule contains: acetylsalicylic acid 25 mg, dipyridamole 200 mg.

Suitable for secondary prevention of ischemic stroke (according to the mechanism of thrombosis) and transient ischemic attacks.

The recommended dose - 1 capsule 2 times a day. Usually take 1 capsule in the morning and 1 capsule in the evening regardless of the meal. The capsules should be swallowed whole without chewing, with a glass of water.

Reported hypersensitivity reactions (rash, urticaria, severe bronchospasm and angioedema) in respect of dipyridamole and in respect of acetylsalicylic acid. In very rare cases after administration of acetylsalicylic acid may be a reduction in the number of platelets (thrombocytopenia). Also reported some cases of thrombocytopenia, observed in the treatment of dipyridamole. Hemorrhages on the skin, such as bruises, bruises, ecchymosis, and hematoma can occur when using the drug.
Adverse effects of dipyridamole at therapeutic doses are usually weak and transient. In the treatment of dipyridamole observed vomiting, diarrhea, and symptoms such as dizziness, nausea, headache, migrenepodobnaya headache (especially at the beginning of treatment), and myalgia. These symptoms usually disappear with prolonged use of the drug. As a consequence of vasodilative effect of dipyridamole may occur hypotension, flushing and tachycardia. Noted worsening symptoms of coronary heart disease.
Acetylsalicylic acid increases bleeding time, and after receiving dipyridamole in very rare cases, there was increased bleeding during and after surgery. When receiving acetylsalicylic acid may occur in the epigastric pain, nausea, vomiting, stomach ulcer or duodenal ulcer and erosive gastritis, which may lead to serious gastrointestinal bleeding. As a result of hidden bleeding, especially when taking aspirin for a long period of time may develop iron deficiency anemia.

Symptoms: due to the ratio of doses of dipyridamole and acetylsalicylic acid in cases of overdose Aggrenox, are likely to be dominated by signs and symptoms of overdose dipyridamole.
Experience with the dipyridamole overdose is limited due to the small number of observations. Presumably, should exhibit such symptoms as hot flashes, flushing, increased sweating, excited state, weakness, dizziness, and symptoms of angina. Maybe a sharp decline in blood pressure and tachycardia.
Symptoms of low acute overdose of acetylsalicylic acid are hyperventilation, ringing in the ears, nausea, vomiting, blurred vision and hearing loss, dizziness, and causing a dreamy consciousness. Dizziness and ringing in the ears, especially among elderly patients, may be symptoms of overdose.
Treatment: perform symptomatically, gastric lavage. Introduction of xanthine derivatives (eg aminophylline) may reverse the hemodynamic effects of dipyridamole overdose. Since dipyridamole is widely distributed in tissues and is mainly eliminated by the liver, it does not appear in hemodialysis.